Game of Thrones: 10 Times Girls Run the World in Season 6

How She Slays: Like many of the strong women on this list, Cersei literally slays on Game of Thrones. In the season six finale, the queen mother finally gets her revenge on the High Sparrow and the Faith of the Seven — she even kills three Tyrells in the process. Cersei loses her last child, Tommen, to suicide, but she barely blinks an eye. Instead, she ascends to take the crown . . . and the Iron Throne.