17 Times Grey's Anatomy Made You the Person You Are Today

And we weep silently as we watch Derek and Callie realize he's gone. We've never needed to give another human a hug worse than we needed to give these two friends one.

By the time Mark dies, he had evolved into one of the most interesting, caring, and beloved characters on the show. The friendship triangle that developed between him, Callie, and Derek is unexpected, but we loved it. Dealing with our own pain over his death is one thing, but having to watch Callie and Derek go through it too . . . brutal.