Zoe Benson is sent to live at Miss Robichaux's Academy for Exceptional Young Ladies in New Orleans after her boyfriend dies in the middle of their makeout session. Her secret power? Magically inducing brain hemorrhaging in any man just by having sex with him. The other girls in the house include Madison Montgomery, a wild child and former film star; Queenie, a descendant of Salem witch Tituba who can inflict wounds on other people by harming herself (without feeling pain); and Nan, a witch who can hear other people's thoughts. All of the girls are hoping to become the next "Supreme," a rare witch who can perform the seven wonders of witchcraft.
The head of Miss Robichaux's Academy, Cordelia Foxx, continually butts heads with her mother, Fiona Goode (the current Supreme), over giving up the title to someone new. But after Zoe and Madison go to a local frat party, where Zoe meets good guy Kyle and Madison is gang-raped by some of his frat brothers, things change. Madison gets revenge by flipping their bus over after they leave, killing Kyle and six others. In addition to trying to prove themselves to Cordelia and Fiona, they also have to worry about Kyle, whom they brought back from the dead by putting together body parts from his dead frat brothers.
