Why it destroyed you: Watching patients die on this show is never easy, and it's harder when the patient is a child. This guileless, laid-back version of Keane's upbeat tune will tear you apart when you watch the doctors at Grey Sloan try in vain to save Winnie, the young victim of a building collapse. The song fades as the doctors give up on resuscitating her. Just as we're freshly primed by this tragedy, Jo tells Alex that she's married.