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Honesty is the foundation of a good friendship, and Cristina and Meredith are very honest with each other. After the awful shooting, Meredith is hesitant to tell Derek about her miscarriage, and Cristina leaps right into a marriage. Meredith isn't entirely convinced that Cristina is ready to be married to Owen, so she tells Cristina that she's her soulmate, not to pull Cristina out of the marriage, but to remind her that she has a friend watching her back.