Meredith Grey's Most Defining Moments on Grey's Anatomy

So Grey's Anatomy has successfully proven that even a small piece of stationery can make you sob tears of unadulterated happiness and devastating heartbreak. In season five, Meredith and Derek give their wedding to Alex and Izzie. Running late for their appointment at City Hall, they improvise by jotting down their vows to each other on a Post-It. Though the gesture is small, it's life-changing. The iconic sticky note has become one of the biggest symbols in the show, last seen in season 14 when Meredith buries it in her drawer beneath some clothes with Derek's ferry cap.