Season 2, Ep. 9: Meredith Has a Heart-to-Heart With Alex
Meredith and Alex don't get off to the best start — he calls her a nurse, and she calls him a frat boy b*tch. But this season two moment shows them having a heart-to-heart while they avoid Izzie's Thanksgiving dinner. In this first moment that they really bond, Meredith talks about her depressive struggles while Alex confesses that he failed the medical boards.