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We all know that being a teenager is rough — and that theme is on full display in animated Netflix Original Big Mouth. In the most recent season, protagonist Andrew navigates his friend Jessi's depression and anxiety, which are portrayed in cartoonish animalistic form by the Depression Kitty and Tito the Anxiety Mosquito, respectively. The fact that these mood disorders each have their own characters highlights just how all-consuming and intrusive and depression and anxiety can be. Big Mouth is perfect for anyone who's looking for a direct, relatable characterization of their mental health symptoms.