Meredith Grey's Most Defining Moments on Grey's Anatomy

I still can't handle this moment even three seasons later just because it's so emotionally raw. "Chasing Cars" playing in the background more or less means fans have to wade through emotional shambles. After getting struck by a car, Derek is soon pronounced brain-dead. Through tears at his bedside, Meredith tells her husband it's OK for him to go. This woman is the embodiment of strength!