This flagship 2005 Shonda Rhimes show has grown into a decades-long pop culture phenomenon, turning her into a household name. Set in a teaching hospital in Seattle, "Grey's Anatomy" follows the professional and personal lives of a group of surgeons, from ambitious young interns to experienced, groundbreaking pros. At the center of it all is Meredith Grey, the daughter of a surgical legend who's looking to get out from under her mother's shadow. Over the course of many years, doctors come and go and lives change forever as these surgeons realize that they can fix pretty much anything (except their own hearts). The series's 19th season premieres this October, with Ellen Pompeo returning as Meredith in a smaller role.
